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Activation of the intrinsic and extrinsic pathways in high pressure-induced apoptosis of murine erythroleukemia cells

We previously demonstrated that caspase-3, an executioner of apoptosis, is activated in the pressure-induced apoptosis of murine erythroleukemia (MEL) cells (at 100 MPa). Here, we examined the pathway of caspase-3 activation using peptide substrates and caspase inhibitors. Using the substrates of ca...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Takeo, Hashiguchi, Kenji, Katsuki, Satoshi, Iwamoto, Wakako, Tsuruhara, Shoichiro, Terada, Shigeyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275616/
https://www.ncbi.nlm.nih.gov/pubmed/17952376
http://dx.doi.org/10.2478/s11658-007-0034-x