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The effects of markedly raised intracellular sphingosine kinase-1 activity in endothelial cells
The enzyme sphingosine kinase-1 (SK1) promotes the formation of sphingosine-1-phosphate (S1P), which is an important survival factor for endothelial cells (EC). Modest increases in intracellular SK1 activity in the EC are known to confer a survival advantage upon the cells. Here, we investigated the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Versita
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275643/ https://www.ncbi.nlm.nih.gov/pubmed/19238331 http://dx.doi.org/10.2478/s11658-009-0008-2 |