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The effects of markedly raised intracellular sphingosine kinase-1 activity in endothelial cells

The enzyme sphingosine kinase-1 (SK1) promotes the formation of sphingosine-1-phosphate (S1P), which is an important survival factor for endothelial cells (EC). Modest increases in intracellular SK1 activity in the EC are known to confer a survival advantage upon the cells. Here, we investigated the...

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Detalles Bibliográficos
Autores principales:	Limaye, Vidya, Vadas, Mathew A., Pitson, Stuart M., Gamble, Jennifer R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SP Versita 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275643/ https://www.ncbi.nlm.nih.gov/pubmed/19238331 http://dx.doi.org/10.2478/s11658-009-0008-2

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