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The knockdown of c-myc expression by RNAi inhibits cell proliferation in human colon cancer HT-29 cells in vitro and in vivo

We investigated the effects of RNA interference-mediated silencing of the c-myc gene on celluar proliferation and apoptosis in human colon cancer HT-29 cells in vitro and in vivo. A small interfering RNA (siRNA) targeting c-myc was designed, the DNA template was synthesized, and the siRNA was obtain...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Ge, Yin-Lin, Tian, Run-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275647/
https://www.ncbi.nlm.nih.gov/pubmed/19183865
http://dx.doi.org/10.2478/s11658-009-0001-9