Leptin regulates MMP-2, TIMP-1 and collagen synthesis via p38 MAPK in HL-1 murine cardiomyocytes

A clear association between obesity and heart failure exists and a significant role for leptin, the product of the obese gene, has been suggested. One aspect of myocardial remodeling which characterizes heart failure is a disruption in the balance of extracellular matrix synthesis and degradation. H...

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Detalles Bibliográficos
Autores principales: Schram, Kristin, De Girolamo, Sabrina, Madani, Siham, Munoz, Diana, Thong, Farah, Sweeney, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2010
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275652/
https://www.ncbi.nlm.nih.gov/pubmed/20683677
http://dx.doi.org/10.2478/s11658-010-0027-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275652/
https://www.ncbi.nlm.nih.gov/pubmed/20683677
http://dx.doi.org/10.2478/s11658-010-0027-z

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