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Molecular cloning and characterization of a novel anti-TLR9 intrabody

Toll-like receptor 9 (TLR9) is a component of the innate immune system, which recognizes the DNA of both pathogens and hosts. Thus, it can drive autoimmune diseases. Intracellular antibodies expressed inside the ER block transitory protein functions by inhibiting the translocation of the protein fro...

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Detalles Bibliográficos
Autores principales: Reimer, Elisa, Somplatzki, Stefan, Zegenhagen, Diana, Hänel, Svenja, Fels, Alina, Bollhorst, Thorsten, Hovest, Ludger Grosse, Bauer, Stefan, Kirschning, Carsten J., Böldicke, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275677/
https://www.ncbi.nlm.nih.gov/pubmed/23893288
http://dx.doi.org/10.2478/s11658-013-0098-8