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Molecular cloning and characterization of a novel anti-TLR9 intrabody
Toll-like receptor 9 (TLR9) is a component of the innate immune system, which recognizes the DNA of both pathogens and hosts. Thus, it can drive autoimmune diseases. Intracellular antibodies expressed inside the ER block transitory protein functions by inhibiting the translocation of the protein fro...
Autores principales: | Reimer, Elisa, Somplatzki, Stefan, Zegenhagen, Diana, Hänel, Svenja, Fels, Alina, Bollhorst, Thorsten, Hovest, Ludger Grosse, Bauer, Stefan, Kirschning, Carsten J., Böldicke, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275677/ https://www.ncbi.nlm.nih.gov/pubmed/23893288 http://dx.doi.org/10.2478/s11658-013-0098-8 |
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