The mitochondria mediate the induction of NOX1 gene expression by aldosterone in an ATF-1-dependent manner

High aldosterone (Ald) levels can induce hypertrophy of vascular smooth muscle cells (VSMCs), which carries high risks of heart failure. A previous study showed that Ald induces hypertrophy of VSMCs by up-regulating NOX1, a catalytic subunit of NADPH oxidase that produces superoxides. However, the p...

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Detalles Bibliográficos
Autores principales: Fu, Yanping, Shi, Gang, Wu, Yong, Kawai, Yasuyuki, Tian, Qing, Yue, Linlin, Xia, Qinjie, Miyamori, Isamu, Fan, Chunyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275679/
https://www.ncbi.nlm.nih.gov/pubmed/21327719
http://dx.doi.org/10.2478/s11658-011-0002-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275679/
https://www.ncbi.nlm.nih.gov/pubmed/21327719
http://dx.doi.org/10.2478/s11658-011-0002-3

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