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Egr2 overexpression in Schwann cells increases myelination frequency in vitro

Schwann cells are key players in peripheral nerve regeneration, and are uniquely capable of remyelinating axons in this context. Schwann cells orchestrate this process via a set of transcription factors. While it has been shown that overexpression of specific genes, e.g. Egr2, upregulates myelin-rel...

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Detalles Bibliográficos
Autores principales: Tammia, Markus, Mi, Ruifa, Sluch, Valentin M., Zhu, Allen, Chung, Tiffany, Shinn, Daniel, Zack, Donald J., Höke, Ahmet, Mao, Hai-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275687/
https://www.ncbi.nlm.nih.gov/pubmed/30761371
http://dx.doi.org/10.1016/j.heliyon.2018.e00982