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Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects
Pharmacological up-regulation of heat shock proteins (hsps) rescues motoneurons from cell death in a mouse model of amyotrophic lateral sclerosis. However, the relationship between increased hsp expression and neuronal survival is not straightforward. Here we examined the effects of two pharmacologi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SP Versita
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275696/ https://www.ncbi.nlm.nih.gov/pubmed/19183864 http://dx.doi.org/10.2478/s11658-009-0002-8 |