A study on the fundamental factors determining the efficacy of siRNAs with high C/G contents

Although there are many reports about the efficacy of siRNAs, it is not clear whether those siRNAs with high C/G contents can be used to silence their target mRNAs efficiently. In this study, we investigated the structure and function of a group of siRNAs with high C/G contents. The results showed t...

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Detalles Bibliográficos
Autores principales: Liao, Jie-Ying, Yin, James Q., Chen, Fang, Liu, Tie-Gang, Yue, Jia-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275720/
https://www.ncbi.nlm.nih.gov/pubmed/18197393
http://dx.doi.org/10.2478/s11658-008-0001-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275720/
https://www.ncbi.nlm.nih.gov/pubmed/18197393
http://dx.doi.org/10.2478/s11658-008-0001-1

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