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A study on the fundamental factors determining the efficacy of siRNAs with high C/G contents
Although there are many reports about the efficacy of siRNAs, it is not clear whether those siRNAs with high C/G contents can be used to silence their target mRNAs efficiently. In this study, we investigated the structure and function of a group of siRNAs with high C/G contents. The results showed t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SP Versita
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275720/ https://www.ncbi.nlm.nih.gov/pubmed/18197393 http://dx.doi.org/10.2478/s11658-008-0001-1 |