Decay of γ-H2AX foci correlates with potentially lethal damage repair and P53 status in human colorectal carcinoma cells

The influence of p53 status on potentially lethal damage repair (PLDR) and DNA double-strand break (DSB) repair was studied in two isogenic human colorectal carcinoma cell lines: RKO (p53 wild-type) and RC10.1 (p53 null). They were treated with different doses of ionizing radiation, and survival and...

Descripción completa

Detalles Bibliográficos
Autores principales: Van Oorschot, Bregje, Oei, Arlene L., Nuijens, Anna C., Rodermond, Hans, Hoeben, Ron, Stap, Jan, Stalpers, Lukas J., Franken, Nicolaas A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275741/
https://www.ncbi.nlm.nih.gov/pubmed/24363165
http://dx.doi.org/10.2478/s11658-013-0113-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275741/
https://www.ncbi.nlm.nih.gov/pubmed/24363165
http://dx.doi.org/10.2478/s11658-013-0113-0

Ejemplares similares