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Decay of γ-H2AX foci correlates with potentially lethal damage repair and P53 status in human colorectal carcinoma cells

The influence of p53 status on potentially lethal damage repair (PLDR) and DNA double-strand break (DSB) repair was studied in two isogenic human colorectal carcinoma cell lines: RKO (p53 wild-type) and RC10.1 (p53 null). They were treated with different doses of ionizing radiation, and survival and...

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Detalles Bibliográficos
Autores principales:	Van Oorschot, Bregje, Oei, Arlene L., Nuijens, Anna C., Rodermond, Hans, Hoeben, Ron, Stap, Jan, Stalpers, Lukas J., Franken, Nicolaas A. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Versita 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275741/ https://www.ncbi.nlm.nih.gov/pubmed/24363165 http://dx.doi.org/10.2478/s11658-013-0113-0

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