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A nanoformulation of siRNA and its role in cancer therapy: In vitro and in vivo evaluation

Overexpression of anti-apoptotic Bcl-2 is often observed in a wide variety of human cancers. It prevents the induction of apoptosis in neoplastic cells and contributes to resistance to chemotherapy. RNA interference has emerged as an efficient and selective technique for gene silencing. The potentia...

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Detalles Bibliográficos
Autores principales: Jagani, Hitesh, Rao, Josyula Venkata, Palanimuthu, Vasanth Raj, Hariharapura, Raghu Chandrashekar, Gang, Sagar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275763/
https://www.ncbi.nlm.nih.gov/pubmed/23271435
http://dx.doi.org/10.2478/s11658-012-0043-2