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A nanoformulation of siRNA and its role in cancer therapy: In vitro and in vivo evaluation
Overexpression of anti-apoptotic Bcl-2 is often observed in a wide variety of human cancers. It prevents the induction of apoptosis in neoplastic cells and contributes to resistance to chemotherapy. RNA interference has emerged as an efficient and selective technique for gene silencing. The potentia...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Versita
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275763/ https://www.ncbi.nlm.nih.gov/pubmed/23271435 http://dx.doi.org/10.2478/s11658-012-0043-2 |