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Gene trapping: An antibody-dependent approach for verifying integration in your favorite gene
Gene trapping is used to introduce genome-wide insertional mutations in embryonic stem cells. Determining the integration site is based on highthroughput PCR, which has inevitable possibilities for mistakes, thus necessitating clone verification prior to the generation of mutant mice. Here, we propo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SP Versita
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275795/ https://www.ncbi.nlm.nih.gov/pubmed/18618084 http://dx.doi.org/10.2478/s11658-008-0028-3 |