Up-regulation of GluN2A-containing NMDA receptor protects cultured cortical neuron cells from oxidative stress

Neuronal excitotoxicity induced by spreading depolarization occurs during multiple brain diseases. The subsequent extensive releasing of neuronal transmitter glutamate results in over activation of the ionic glutamate receptors and then triggers neuronal cell death. The N-methyl-D-aspartate (NMDA) r...

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Detalles Bibliográficos
Autores principales: Zhu, Jia, Xu, Shilian, Li, Shengpei, Yang, Xueling, Yu, Xianhui, Zhang, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275848/
https://www.ncbi.nlm.nih.gov/pubmed/30555952
http://dx.doi.org/10.1016/j.heliyon.2018.e00976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275848/
https://www.ncbi.nlm.nih.gov/pubmed/30555952
http://dx.doi.org/10.1016/j.heliyon.2018.e00976

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