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Up-regulation of GluN2A-containing NMDA receptor protects cultured cortical neuron cells from oxidative stress
Neuronal excitotoxicity induced by spreading depolarization occurs during multiple brain diseases. The subsequent extensive releasing of neuronal transmitter glutamate results in over activation of the ionic glutamate receptors and then triggers neuronal cell death. The N-methyl-D-aspartate (NMDA) r...
Autores principales: | Zhu, Jia, Xu, Shilian, Li, Shengpei, Yang, Xueling, Yu, Xianhui, Zhang, Xiaomin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275848/ https://www.ncbi.nlm.nih.gov/pubmed/30555952 http://dx.doi.org/10.1016/j.heliyon.2018.e00976 |
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