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p600 stabilizes microtubules to prevent the aggregation of CaMKIIα during photoconductive stimulation
The large microtubule-associated/Ca(2+)-signalling protein p600 (also known as UBR4) is required for hippocampal neuronal survival upon Ca(2+) dyshomeostasis induced by glutamate treatment. During this process, p600 prevents aggregation of the Ca(2+)/calmodulin-dependent kinase IIα (CaMKIIα), a prox...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Versita
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275876/ https://www.ncbi.nlm.nih.gov/pubmed/25034033 http://dx.doi.org/10.2478/s11658-014-0201-9 |