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p600 stabilizes microtubules to prevent the aggregation of CaMKIIα during photoconductive stimulation

The large microtubule-associated/Ca(2+)-signalling protein p600 (also known as UBR4) is required for hippocampal neuronal survival upon Ca(2+) dyshomeostasis induced by glutamate treatment. During this process, p600 prevents aggregation of the Ca(2+)/calmodulin-dependent kinase IIα (CaMKIIα), a prox...

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Detalles Bibliográficos
Autores principales: Belzil, Camille, Ramos, Tim, Sanada, Kamon, Colicos, Michael A., Nguyen, Minh Dang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275876/
https://www.ncbi.nlm.nih.gov/pubmed/25034033
http://dx.doi.org/10.2478/s11658-014-0201-9

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