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A functional analysis of G23A polymorphism and the alternative splicing in the expression of the XPA gene

The XPA gene has a commonly occurring polymorphism (G23A) associated with cancer risk. This study assessed the functional significance of this polymorphism, which is localised near the translation start codon. Lymphoblastoid cell lines with alternative homozygous genotypes showed no significant diff...

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Detalles Bibliográficos
Autores principales: Butkiewicz, Dorota, Krześniak, Małgorzata, Vaitiekunaite, Rasa, Sikora, Bożena, Bowman, Elise D., Harris, Curtis C., Rusin, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275895/
https://www.ncbi.nlm.nih.gov/pubmed/20865363
http://dx.doi.org/10.2478/s11658-010-0032-2