Doxorubicin-transferrin conjugate selectively overcomes multidrug resistance in leukaemia cells

Neoplastic cells frequently have an increased number of transferrin receptors. Coupling transferrin to an anti-neoplastic drug has the potential to overcome multidrug resistance (MDR). The purpose of this study was to examine the distribution and action of doxorubicin-transferrin conjugate (DOXTRF)...

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Detalles Bibliográficos
Autores principales: Łubgan, Dorota, Jóźwiak, Zofia, Grabenbauer, Gerhard G., Distel, Luitpold V. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275917/
https://www.ncbi.nlm.nih.gov/pubmed/18850074
http://dx.doi.org/10.2478/s11658-008-0037-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275917/
https://www.ncbi.nlm.nih.gov/pubmed/18850074
http://dx.doi.org/10.2478/s11658-008-0037-2

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