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Doxorubicin-transferrin conjugate selectively overcomes multidrug resistance in leukaemia cells
Neoplastic cells frequently have an increased number of transferrin receptors. Coupling transferrin to an anti-neoplastic drug has the potential to overcome multidrug resistance (MDR). The purpose of this study was to examine the distribution and action of doxorubicin-transferrin conjugate (DOXTRF)...
Autores principales: | Łubgan, Dorota, Jóźwiak, Zofia, Grabenbauer, Gerhard G., Distel, Luitpold V. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Versita
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275917/ https://www.ncbi.nlm.nih.gov/pubmed/18850074 http://dx.doi.org/10.2478/s11658-008-0037-2 |
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