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Treatment with TNF-α and IFN-γ alters the activation of SER/THR protein kinases and the metabolic response to IGF-I in mouse c2c12 myogenic cells

The aim of this study was to compare the effects of TNF-α, IL-1β and IFN-γ on the activation of protein kinase B (PKB), p70(S6k), mitogen-activated protein kinase (MAPK) and p90(rsk), and on IGF-I-stimulated glucose uptake and protein synthesis in mouse C2C12 myotubes. 100 nmol/l IGF-I stimulated gl...

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Detalles Bibliográficos
Autores principales: Grzelkowska-Kowalczyk, Katarzyna, Wieteska-Skrzeczyńska, Wioletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275934/
https://www.ncbi.nlm.nih.gov/pubmed/19685010
http://dx.doi.org/10.2478/s11658-009-0033-1