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Targeted cationic poly(D,L-lactic-co-glycolic acid) nanoparticles for gene delivery to cultured cells

We developed a new targeted cationic nanoparticulate system composed of poly(D,L-lactic-co-glycolic acid) (PLGA), 1,2-dioleoyl-3-(trimethylammonium) propane (DOTAP) and asialofetuin (AF), and found it to be a highly effective formulation for gene delivery to liver tumor cells. The nanoparticles (NP)...

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Detalles Bibliográficos
Autores principales: Díez, Sonsoles, Miguéliz, Itziar, Tros de Ilarduya, Conchita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275944/
https://www.ncbi.nlm.nih.gov/pubmed/19194666
http://dx.doi.org/10.2478/s11658-009-0003-7