Cargando…

Inhibitor-2 induced M-phase arrest in Xenopus cycling egg extracts is dependent on MAPK activation

The evolutionarily-conserved protein phosphatase 1 (PP1) plays a central role in dephosphorylation of phosphoproteins during the M phase of the cell cycle. We demonstrate here that the PP1 inhibitor inhibitor-2 protein (Inh-2) induces an M-phase arrest in Xenopus cycling egg extracts. Interestingly,...

Descripción completa

Detalles Bibliográficos
Autores principales: Khandani, Arian, Mohtashami, Mahmood, Camirand, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275968/
https://www.ncbi.nlm.nih.gov/pubmed/21956525
http://dx.doi.org/10.2478/s11658-011-0030-z