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Rho kinase inhibitors stimulate the migration of human cultured osteoblastic cells by regulating actomyosin activity

We investigated the effects of Rho-associated kinase (ROCK) on migration and cytoskeletal organization in primary human osteoblasts and Saos-2 human osteosarcoma cells. Both cell types were exposed to two different ROCK inhibitors, Y-27632 and HA-1077. In the improved motility assay used in the pres...

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Detalles Bibliográficos
Autores principales: Zhang, Xuejiao, Li, Cheng, Gao, Huiling, Nabeka, Hiroaki, Shimokawa, Tetsuya, Wakisaka, Hiroyuki, Matsuda, Seiji, Kobayashi, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275969/
https://www.ncbi.nlm.nih.gov/pubmed/21394446
http://dx.doi.org/10.2478/s11658-011-0006-z