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Effects of Clostridium perfringens enterotoxin via claudin-4 on normal human pancreatic duct epithelial cells and cancer cells

The tight junction protein claudin-4 is frequently overexpressed in pancreatic cancer, and is also a receptor for Clostridium perfringens enterotoxin (CPE). The cytotoxic effects of CPE are thought to be useful as a novel therapeutic tool for pancreatic cancer. However, the responses to CPE via clau...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Hiroshi, Kojima, Takashi, Ito, Tatsuya, Kyuno, Daisuke, Kimura, Yasutoshi, Imamura, Masafumi, Hirata, Koichi, Sawada, Norimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275971/
https://www.ncbi.nlm.nih.gov/pubmed/21573709
http://dx.doi.org/10.2478/s11658-011-0014-z