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Perturbation of the lipid phase of a membrane is not involved in the modulation of MRP1 transport activity by flavonoids
The expression of transmembrane transporter multidrug resistance-associated protein 1 (MRP1) confers the multidrug-resistant phenotype (MDR) on cancer cells. Since the activity of the other MDR transporter, P-glycoprotein, is sensitive to membrane perturbation, we aimed to check whether the changes...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Versita
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275984/ https://www.ncbi.nlm.nih.gov/pubmed/19020811 http://dx.doi.org/10.2478/s11658-008-0044-3 |