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Direct Rho-associated kinase inhibiton induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells

Axons fail to regenerate in the adult central nervous system (CNS) following injury. Developing strategies to promote axonal regeneration is therapeutically attractive for various CNS pathologies such as traumatic brain injury, stroke and Alzheimer’s disease. Because the RhoA pathway is involved in...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiqun, Ottens, Andrew K., Larner, Stephen F., Kobeissy, Firas H., Williams, Melissa L., Hayes, Ronald L., Wang, Kevin K. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276008/
https://www.ncbi.nlm.nih.gov/pubmed/16847745
http://dx.doi.org/10.2478/s11658-006-0002-x