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Direct Rho-associated kinase inhibiton induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells
Axons fail to regenerate in the adult central nervous system (CNS) following injury. Developing strategies to promote axonal regeneration is therapeutically attractive for various CNS pathologies such as traumatic brain injury, stroke and Alzheimer’s disease. Because the RhoA pathway is involved in...
Autores principales: | Zhang, Zhiqun, Ottens, Andrew K., Larner, Stephen F., Kobeissy, Firas H., Williams, Melissa L., Hayes, Ronald L., Wang, Kevin K. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Versita
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276008/ https://www.ncbi.nlm.nih.gov/pubmed/16847745 http://dx.doi.org/10.2478/s11658-006-0002-x |
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