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S-nitrosoglutathione modulates CXCR4 and ICOS expression

The expression of CXCR4, a membrane protein which is involved in the entry of HIV-1, is down-modulated from the cell surface by Phorbol 12-myristate 13-acetate (PMA) and the Ca+ ionophore, Ionomycin. Inducible co-stimulator (ICOS), which contributes to lymphocyte proliferation, is up-regulated by PM...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yoshihiko, Pahwa, Rajendra, Pahwa, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276017/
https://www.ncbi.nlm.nih.gov/pubmed/16847746
http://dx.doi.org/10.2478/s11658-006-0003-9