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Downregulation of KDR expression induces apoptosis in breast cancer cells

Angiogenesis plays a crucial role in the growth, invasion and metastasis of breast cancer. Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are the key regulators of tumor angiogenesis. VEGFR-2, known as the kinase insert domain receptor (KDR), is a key receptor involved in m...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Ge, Yin-Lin, Zhang, Shu-Ping, Yan, Ping, Tian, Run-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276020/
https://www.ncbi.nlm.nih.gov/pubmed/25182240
http://dx.doi.org/10.2478/s11658-014-0210-8