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Ketamine Corrects a Deficit in Reversal Learning Caused by Chronic Intermittent Cold Stress in Female Rats

BACKGROUND: Individuals with stress-related psychiatric disorders exhibit deficits in cognitive flexibility. We have shown that chronic intermittent cold stress induces deficits in reversal learning, a form of cognitive flexibility mediated in the orbitofrontal cortex, that was reversed by ketamine...

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Detalles Bibliográficos
Autores principales: Paredes, Denisse, Silva, Jeri D, Morilak, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276029/
https://www.ncbi.nlm.nih.gov/pubmed/30169648
http://dx.doi.org/10.1093/ijnp/pyy080