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On-substrate Enzymatic Reaction to Determine Acetylcholinesterase Activity in Whole Blood by Paper Spray Mass Spectrometry

Currently, all assays measuring acetylcholinesterase (AChE) activity following a suspected nerve agent exposure leverage methodologies that fail to identify the agent. This limits the overall effectiveness and ability to administer proper countermeasures. As such, there is an urgent need to identify...

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Detalles Bibliográficos
Autores principales: Carmany, Daniel O., Mach, Phillip M., Rizzo, Gabrielle M., Dhummakupt, Elizabeth S., McBride, Ethan M., Sekowski, Jennifer W., Benton, Bernard, Demond, Paul S., Busch, Michael W., Glaros, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276064/
https://www.ncbi.nlm.nih.gov/pubmed/30280314
http://dx.doi.org/10.1007/s13361-018-2072-1