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Comparing Hydrogen Deuterium Exchange and Fast Photochemical Oxidation of Proteins: a Structural Characterisation of Wild-Type and ΔN6 β(2)-Microglobulin
Hydrogen deuterium exchange (HDX) coupled to mass spectrometry (MS) is a well-established technique employed in the field of structural MS to probe the solvent accessibility, dynamics and hydrogen bonding of backbone amides in proteins. By contrast, fast photochemical oxidation of proteins (FPOP) us...
Autores principales: | Cornwell, Owen, Radford, Sheena E., Ashcroft, Alison E., Ault, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276068/ https://www.ncbi.nlm.nih.gov/pubmed/30267362 http://dx.doi.org/10.1007/s13361-018-2067-y |
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