MICAL2 Mediates p53 Ubiquitin Degradation through Oxidating p53 Methionine 40 and 160 and Promotes Colorectal Cancer Malignance

Molecule interacting with CasL2 (MICAL2), a microtubule-associated monooxygenase, is highly expressed in various cancers and is involved in cancer pathogenesis, but the mechanisms underlying its regulation in carcinogenesis are unclear. In this study, we aim to clarify the mechanism by which MICAL2...

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Detalles Bibliográficos
Autores principales: Lu, Jinping, Li, Yuejin, Wu, Yuanzhong, Zhou, Shan, Duan, Chaojun, Dong, Zigang, Kang, Tiebang, Tang, Faqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276083/
https://www.ncbi.nlm.nih.gov/pubmed/30555547
http://dx.doi.org/10.7150/thno.28228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276083/
https://www.ncbi.nlm.nih.gov/pubmed/30555547
http://dx.doi.org/10.7150/thno.28228

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