V-ATPases and osteoclasts: ambiguous future of V-ATPases inhibitors in osteoporosis

Vacuolar ATPases (V-ATPases) play a critical role in regulating extracellular acidification of osteoclasts and bone resorption. The deficiencies of subunit a3 and d2 of V-ATPases result in increased bone density in humans and mice. One of the traditional drug design strategies in treating osteoporos...

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Detalles Bibliográficos
Autores principales: Duan, Xiaohong, Yang, Shaoqing, Zhang, Lei, Yang, Tielin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276090/
https://www.ncbi.nlm.nih.gov/pubmed/30555553
http://dx.doi.org/10.7150/thno.28391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276090/
https://www.ncbi.nlm.nih.gov/pubmed/30555553
http://dx.doi.org/10.7150/thno.28391

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