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Increasing lean muscle mass in mice via nanoparticle-mediated hepatic delivery of follistatin mRNA

Muscle atrophy occurs during chronic diseases, resulting in diminished quality of life and compromised treatment outcomes. There is a high demand for therapeutics that increase muscle mass while abrogating the need for special dietary and exercise requirements. Therefore, we developed an efficient n...

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Detalles Bibliográficos
Autores principales: Schumann, Canan, Nguyen, Duc X., Norgard, Mason, Bortnyak, Yulia, Korzun, Tetiana, Chan, Stephanie, Lorenz, Anna St., Moses, Abraham S., Albarqi, Hassan A., Wong, Leon, Michaelis, Katherine, Zhu, Xinxia, Alani, Adam W. G., Taratula, Olena R., Krasnow, Stephanie, Marks, Daniel L., Taratula, Oleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276093/
https://www.ncbi.nlm.nih.gov/pubmed/30555546
http://dx.doi.org/10.7150/thno.27847