Cargando…

Microglial TLR4-dependent autophagy induces ischemic white matter damage via STAT1/6 pathway

Rationale: Ischemic white matter damage frequently results in myelin loss, accompanied with microglial activation. We previously found that directing microglia towards an anti-inflammatory phenotype provided a beneficial microenvironment and helped maintain white matter integrity during chronic cere...

Descripción completa

Detalles Bibliográficos
Autores principales: Qin, Chuan, Liu, Qian, Hu, Zi-Wei, Zhou, Luo-Qi, Shang, Ke, Bosco, Dale B., Wu, Long-Jun, Tian, Dai-Shi, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276098/
https://www.ncbi.nlm.nih.gov/pubmed/30555556
http://dx.doi.org/10.7150/thno.27882