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Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication

BACKGROUND: The influenza matrix protein (M1) layer under the viral membrane plays multiple roles in virus assembly and infection. N-domain and C-domain are connected by a loop region, which consists of conserved RQMV motif. METHODS: The function of the highly conserve RQMV motif in the influenza vi...

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Detalles Bibliográficos
Autores principales: Švančarová, Petra, Betáková, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276163/
https://www.ncbi.nlm.nih.gov/pubmed/30509291
http://dx.doi.org/10.1186/s12985-018-1056-x