Cargando…

The STRIPAK complex components FAM40A and FAM40B regulate endothelial cell contractility via ROCKs

BACKGROUND: Endothelial cells provide a barrier between blood and tissues, which is regulated to allow molecules and cells in out of tissues. Patients with cerebral cavernous malformations (CCM) have dilated leaky blood vessels, especially in the central nervous system. A subset of these patients ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Suryavanshi, Narendra, Furmston, Joanna, Ridley, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276190/
https://www.ncbi.nlm.nih.gov/pubmed/30509168
http://dx.doi.org/10.1186/s12860-018-0175-y