p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant

BACKGROUND: In response to oncogenic stress, the tumour suppressor protein p53 can induce the elimination of cells through induction of cell death or senescence, helping to restrain malignant progression. Conversely, under nutrient stress, p53 can protect cells by supporting metabolic adaptation. Ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Humpton, Timothy J., Hock, Andreas K., Maddocks, Oliver D. K., Vousden, Karen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276204/
https://www.ncbi.nlm.nih.gov/pubmed/30524726
http://dx.doi.org/10.1186/s40170-018-0191-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276204/
https://www.ncbi.nlm.nih.gov/pubmed/30524726
http://dx.doi.org/10.1186/s40170-018-0191-6

Ejemplares similares