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Molecular analysis of NPAS3 functional domains and variants

BACKGROUND: NPAS3 encodes a transcription factor which has been associated with multiple human psychiatric and neurodevelopmental disorders. In mice, deletion of Npas3 was found to cause alterations in neurodevelopment, as well as a marked reduction in neurogenesis in the adult mouse hippocampus. Th...

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Detalles Bibliográficos
Autores principales: Luoma, Leiah M., Berry, Fred B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276216/
https://www.ncbi.nlm.nih.gov/pubmed/30509165
http://dx.doi.org/10.1186/s12867-018-0117-4