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Understanding tumor ecosystems by single-cell sequencing: promises and limitations

Cellular heterogeneity within and across tumors has been a major obstacle in understanding and treating cancer, and the complex heterogeneity is masked if bulk tumor tissues are used for analysis. The advent of rapidly developing single-cell sequencing technologies, which include methods related to...

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Detalles Bibliográficos
Autores principales: Ren, Xianwen, Kang, Boxi, Zhang, Zemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276232/
https://www.ncbi.nlm.nih.gov/pubmed/30509292
http://dx.doi.org/10.1186/s13059-018-1593-z