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Understanding tumor ecosystems by single-cell sequencing: promises and limitations
Cellular heterogeneity within and across tumors has been a major obstacle in understanding and treating cancer, and the complex heterogeneity is masked if bulk tumor tissues are used for analysis. The advent of rapidly developing single-cell sequencing technologies, which include methods related to...
Autores principales: | Ren, Xianwen, Kang, Boxi, Zhang, Zemin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276232/ https://www.ncbi.nlm.nih.gov/pubmed/30509292 http://dx.doi.org/10.1186/s13059-018-1593-z |
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