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Full-length title: NRPPUR database search and in vitro analysis identify an NRPS-PKS biosynthetic gene cluster with a potential antibiotic effect

BACKGROUND: Growing concern about the emergence of antibiotic resistance is compelling the pharmaceutical industry to search for new antimicrobial agents. The availability of genome sequences has enabled the development of computational mining as an important tool in the discovery of natural product...

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Detalles Bibliográficos
Autores principales: Fritz, Shirley, Rajaonison, Andriamiharimamy, Chabrol, Olivier, Raoult, Didier, Rolain, Jean-Marc, Merhej, Vicky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276269/
https://www.ncbi.nlm.nih.gov/pubmed/30509188
http://dx.doi.org/10.1186/s12859-018-2479-5