Engineered RNase P Ribozymes Effectively Inhibit the Infection of Murine Cytomegalovirus in Animals

Rationales: Gene-targeting ribozymes represent promising nucleic acid-based gene interference agents for therapeutic application. We previously used an in vitro selection procedure to engineer novel RNase P-based ribozyme variants with enhanced targeting activity. However, it has not been reported w...

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Detalles Bibliográficos
Autores principales: Li, Wei, Liu, Yujun, Wang, Yuanyuan, Li, Ruilin, Trang, Phong, Tang, Wei, Yang, Zhu, Wang, Yu, Sun, Xu, Xing, Xiwen, Lu, Sangwei, Liu, Fenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276291/
https://www.ncbi.nlm.nih.gov/pubmed/30555569
http://dx.doi.org/10.7150/thno.27776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276291/
https://www.ncbi.nlm.nih.gov/pubmed/30555569
http://dx.doi.org/10.7150/thno.27776

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