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Engineered RNase P Ribozymes Effectively Inhibit the Infection of Murine Cytomegalovirus in Animals
Rationales: Gene-targeting ribozymes represent promising nucleic acid-based gene interference agents for therapeutic application. We previously used an in vitro selection procedure to engineer novel RNase P-based ribozyme variants with enhanced targeting activity. However, it has not been reported w...
Autores principales: | Li, Wei, Liu, Yujun, Wang, Yuanyuan, Li, Ruilin, Trang, Phong, Tang, Wei, Yang, Zhu, Wang, Yu, Sun, Xu, Xing, Xiwen, Lu, Sangwei, Liu, Fenyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276291/ https://www.ncbi.nlm.nih.gov/pubmed/30555569 http://dx.doi.org/10.7150/thno.27776 |
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